Acetylcholine Neurotransmitter Receptor Densities in the Striatum of Hemiparkinsonian Rats Following Botulinum Neurotoxin-A Injection

• Main Authors: Teresa Mann (Author), Karl Zilles (Author), Felix Klawitter (Author), Markus Cremer (Author), Alexander Hawlitschka (Author), Nicola Palomero-Gallagher (Author), Oliver Schmitt (Author), Andreas Wree (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cholinergic neurotransmission has a pivotal function in the caudate-putamen, and is highly associated with the pathophysiology of Parkinson's disease. Here, we investigated long-term changes in the densities of the muscarinic receptor subtypes M1, M2, M3 (mAchRs) and the nicotinic receptor subt...