Efficacy of Apremilast Gels in Mouse Model of Imiquimod-Induced Psoriasis Skin Inflammation

• Hoofdauteurs: Marcelle Silva-Abreu (Auteur), Lilian Sosa (Auteur), Lupe Carolina Espinoza (Auteur), María-José Fábrega (Auteur), María J. Rodríguez-Lagunas (Auteur), Mireia Mallandrich (Auteur), Ana Cristina Calpena (Auteur), María Luisa Garduño-Ramírez (Auteur), María Rincón (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Apremilast (APM) is a novel drug for the treatment of psoriasis and psoriatic arthritis. APM is a phosphodiesterase 4 (PDE4) inhibitor, raising intracellular cAMP levels and thereby decreasing the inflammatory response by modulating the expression of TNF-α, IL-17, IL-23, and other inflammatory cytok...