High-Efficacy α,β-Dehydromonacolin S Improves Hepatic Steatosis and Suppresses Gluconeogenesis Pathway in High-Fat Diet-Induced Obese Rats

• Autori principali: Jutatip Kaewmalee (Autore), Atcharaporn Ontawong (Autore), Acharaporn Duangjai (Autore), Chittreeya Tansakul (Autore), Vatcharin Rukachaisirikul (Autore), Chatchai Muanprasat (Autore), Chutima Srimaroeng (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Isolated α,β-dehydromonacolin S (<i>C5</i>) from soil-derived fungus <i>Aspergillus sclerotiorum</i> PSU-RSPG178 was recently shown to exhibit an inhibitory effect against 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity in vitro. In this study, we investigated...