Posaconazole inhibits the stemness of cancer stem-like cells by inducing autophagy and suppressing the Wnt/β-catenin/survivin signaling pathway in glioblastoma

Posaconazole (POS) has been reported to present potential antitumor activity for glioblastoma (GBM). However, its molecular mechanisms remain unclear. In this study, we found that POS has potent cytotoxicity and inhibits cell viability and proliferation in GBM. In addition, we adopted a sphere forma...

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Main Authors: Hua Wang (Author), Yinfeng Tan (Author), Hao Jia (Author), Danqi Liu (Author), Rangru Liu (Author)
Format: Book
Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
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3rd Floor Main Library

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