Primary skeletal muscle cells from chronic kidney disease patients retain hallmarks of cachexia in vitro

• Main Authors: Luke A. Baker (Author), Thomas F. O'Sullivan (Author), Katherine A. Robinson (Author), Matthew P.M. Graham‐Brown (Author), Rupert W. Major (Author), Robert U. Ashford (Author), Alice C. Smith (Author), Andrew Philp (Author), Emma L. Watson (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Skeletal muscle wasting and dysfunction are common characteristics noted in people who suffer from chronic kidney disease (CKD). The mechanisms by which this occurs are complex, and although progress has been made, the key underpinning mechanisms are not yet fully elucidated. Wit...