Quantification of sibutramine and its two metabolites in human plasma by LCâESI-MS/MS and its application in a bioequivalence study

• Main Authors: Venkata Suresh Ponnuru (Author), B.R. Challa (Author), RamaRao Nadendla (Author)
• 格式: 图书
• 出版: Elsevier, 2012-08-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Obesity can be considered as a chronic illness of epidemic proportion and its incidents have increased exponentially in recent years. The use of anti-obesity drugs such as sibutramine is somewhat helpful. There is a need to quantify such drugs in biological samples, which is generally quite difficul...