Quantification of sibutramine and its two metabolites in human plasma by LCâESI-MS/MS and its application in a bioequivalence study

Obesity can be considered as a chronic illness of epidemic proportion and its incidents have increased exponentially in recent years. The use of anti-obesity drugs such as sibutramine is somewhat helpful. There is a need to quantify such drugs in biological samples, which is generally quite difficul...

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Main Authors: Venkata Suresh Ponnuru (Author), B.R. Challa (Author), RamaRao Nadendla (Author)
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出版: Elsevier, 2012-08-01T00:00:00Z.
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索引号: A1234.567
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