Mesangial matrix expansion in a novel mouse model of diabetic kidney disease associated with the metabolic syndrome

• Main Authors: Elisabet Van Loon (Author), Joseph Pierre Aboumsallem (Author), Evelyne Lerut (Author), Marija Bogojevic (Author), Aleksandar Denic (Author), Walter Park (Author), Ilayaraja Muthuramu (Author), Mudit Mishra (Author), Mark Stegall (Author), Maarten Naesens (Author), Bart De Geest (Author)
• Format: Book
• Published: Society of Diabetic Nephropathy Prevention, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The evolution of structural changes of diabetic nephropathy in human kidneys is not well documented. Instead, rodent models are used to study diabetic nephropathy in greater detail. However, all rodent models to date are subject to important limitations, and not representative for the...