Aspirin and Some Other Nonsteroidal Anti-Inflammatory Drugs Inhibit Cystic Fibrosis Transmembrane Conductance Regulator Protein Gene Expression in T-84 Cells

• Main Authors: Danielle Tondelier (Author), Franck Brouillard (Author), Joanna Lipecka (Author), Régis Labarthe (Author), Moëz Bali (Author), Marie-Ayliette Costa De Beauregard (Author), Tanja Torossi (Author), Marc Cougnon (Author), Aleksander Edelman (Author), Maryvonne Baudouin-Legros (Author)
• Format: Book
• Published: Hindawi Limited, 1999-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis (CF) is caused by mutations in the CF gene, which encodes CF transmembrane conductance regulator protein (CFTR), a transmembrane protein that acts as a cAMP-regulated chloride channel. The disease is characterized by inflammation but the relationship between inflammation, abnormal tr...