Protective effect of empagliflozin against palmitate-induced lipotoxicity through AMPK in H9c2 cells

• Main Authors: Min-Woo Song (Author), Wenhao Cui (Author), Chang-Gun Lee (Author), Rihua Cui (Author), Young Ho Son (Author), Young Ha Kim (Author), Yujin Kim (Author), Hae Jin Kim (Author), Sung-E. Choi (Author), Yup Kang (Author), Tae Ho Kim (Author), Ja Young Jeon (Author), Kwan-Woo Lee (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sodium-glucose cotransporter 2 (SGLT2) inhibitors have recently emerged as novel cardioprotective agents. However, their direct impact on cardiomyocyte injury is yet to be studied. In this work, we investigate the underlying molecular mechanisms of empagliflozin (EMPA), an SGLT2 inhibitor, in mitiga...