Impact of relative dose intensity on bone marrow suppression induced by S-1: retrospective observational study

• 主要な著者: Toshinori Hirai (著者), Ryuichi Ogawa (著者), Ryosuke Yamaga (著者), Toshimasa Itoh (著者)
• フォーマット: 図書
• 出版事項: BMC, 2018-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background S-1 (a combination of tegafur, gimeracil, and oteracil) is used to treat various cancers. Bone marrow suppression is a dose-limiting toxicity of S-1. The relationship between relative dose intensity (RDI) and bone marrow suppression has not been investigated. Hence, we aimed to e...