Thrombin-Stimulated Proliferation of Cultured Human Synovial Fibroblasts Through Proteolytic Activation of Proteinase-Activated Receptor-1

We examined the mechanism of thrombin on proliferation of synovial fibroblasts obtained from rheumatoid arthritis (RA). Thrombin concentration-dependently induced proliferation of synovial fibroblasts. Proliferation in response to thrombin (10 U /ml) was completely blocked by hirudin. TP367 and TP50...

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Main Authors: Ikue Furuhashi (Author), Kazuki Abe (Author), Toshitsugu Sato (Author), Hideo Inoue (Author)
Format: Book
Published: Elsevier, 2008-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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