Thrombin-Stimulated Proliferation of Cultured Human Synovial Fibroblasts Through Proteolytic Activation of Proteinase-Activated Receptor-1
We examined the mechanism of thrombin on proliferation of synovial fibroblasts obtained from rheumatoid arthritis (RA). Thrombin concentration-dependently induced proliferation of synovial fibroblasts. Proliferation in response to thrombin (10 U /ml) was completely blocked by hirudin. TP367 and TP50...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Elsevier,
2008-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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