Randomized, placebo‐controlled study on the effects of intravenous GSK3858279 (anti‐CCL17) on a battery of evoked pain tests in healthy participants

• Main Authors: Yvonne Boyle (Author), Hemme J. Hijma (Author), Jamie Rees (Author), Jagtar Nijjar (Author), Eirini Panoilia (Author), Yolanda Alvarez (Author), Sarah Siederer (Author), Emma Greening (Author), Edward Emery (Author), Kathy Abbott Banner (Author), Geert Jan Groeneveld (Author)
• פורמט: ספר
• יצא לאור: Wiley, 2024-09-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract C-C Motif Chemokine Ligand 17 (CCL17) is a chemokine that binds and signals through the G‐protein coupled CC‐chemokine receptor 4 and has been implicated in the development of inflammatory and arthritic pain. GSK3858279 is a high‐affinity, first‐in‐class, monoclonal antibody, binding specif...