Pantothenate kinase-associated neurodegeneration: Clinical aspects, diagnosis and treatments

• Main Authors: Saeed Razmeh (Author), Amir Hassan Habibi (Author), Maryam Orooji (Author), Elham Alizadeh (Author), Karim Moradiankokhdan (Author), Behroz Razmeh (Author)
• Format: Book
• Published: MDPI AG, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pantothenate Kinase-Associated Neurodegeneration (PKAN) is an autosomal recessive disorder characterized by a mutation in the PANK2 gene. The clinical presentation may range from only speech disorder to severe generalized dystonia, spasticity, Visual loss, dysphagia and dementia. The hallmark of thi...