Hepatotoxic effects of aristolochic acid: mechanisms and implications

• Main Authors: Qian Zhang (Author), Jiayun Chen (Author), Hengkai He (Author), Wentong Zhao (Author), Yinkwan Wong (Author), Wenhui Li (Author), Sha Feng (Author), Bin Liu (Author), Jigang Wang (Author), Piao Luo (Author)
• Format: Book
• Published: Compuscript Ltd, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Herbal plants that contain aristolochic acids (AAs) have been widely used for medicinal purposes for centuries. However, human exposure to AAs via herbal or dietary intake is thought to be a causative factor for aristolochic acid nephropathy (AAN), hepatotoxic effects, and carcinomas. At present, th...