Icariin improves oxidative stress injury during ischemic stroke via inhibiting mPTP opening

• Main Authors: Zhiyong Zhou (Author), Weili Li (Author), Lu Ni (Author), Tianlun Wang (Author), Yan Huang (Author), Yuanqi Yu (Author), Mingxin Hu (Author), Yinling Liu (Author), Jin'e Wang (Author), Xiaofei Huang (Author), Yanyan Wang (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ischemic stroke presents a significant threat to human health due to its high disability rate and mortality. Currently, the clinical treatment drug, rt-PA, has a narrow therapeutic window and carries a high risk of bleeding. There is an urgent need to find new effective therapeut...