Interleukin (IL)-4 Induces Leukocyte Infiltration In Vivo by an Indirect Mechanism

• Main Authors: Claude Ratthé (Author), Jamila Ennaciri (Author), David M. Garcês Gonçalves (Author), Sonia Chiasson (Author), Denis Girard (Author)
• Format: Book
• Published: Hindawi Limited, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin (IL)-4 is a cytokine known mainly for its anti-inflammatory activity. Using the in vivo murine air pouch model, we found that IL-4 significantly increased the number of leukocytes after 9 hours of treatment, consisting mainly of neutrophil (60%) and monocytic (40%) cell populations. Usin...