Overexpression of toll-like receptor 9 correlates with podocyte injury in a murine model of autoimmune membranoproliferative glomerulonephritis

• Main Authors: Md. Abdul Masum (Author), Osamu Ichii (Author), Yaser Hosny Ali Elewa (Author), Teppei Nakamura (Author), Yuki Otani (Author), Marina Hosotani (Author), Yasuhiro Kon (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toll-like receptors (Tlrs) are sensors of danger signals which promote the activation of immune cells and intrinsic renal cells. Podocytes, the intrinsic cells of glomerulus, are continuously exposed to various plasma solutes and danger signals due to their unique location in the glomerulus. Herein,...