Neuroprotection of NRF2 against Ferroptosis after Traumatic Brain Injury in Mice

• Main Authors: Hao Cheng (Author), Pengfei Wang (Author), Ning Wang (Author), Wenwen Dong (Author), Ziyuan Chen (Author), Mingzhe Wu (Author), Ziwei Wang (Author), Ziqi Yu (Author), Dawei Guan (Author), Linlin Wang (Author), Rui Zhao (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis and iron-related redox imbalance aggravate traumatic brain injury (TBI) outcomes. NRF2 is the predominant transcription factor regulating oxidative stress and neuroinflammation in TBI, but its role in iron-induced post-TBI damage is unclear. We investigated ferroptotic neuronal damage in...