Exosomal PSM-E inhibits macrophage M2 polarization to suppress prostate cancer metastasis through the RACK1 signaling axis

• Main Authors: Xingliang Qin (Author), Rouxi Niu (Author), Yongyao Tan (Author), Yuxin Huang (Author), Weishu Ren (Author), Weiwei Zhou (Author), Huiquan Wu (Author), Junlong Zhang (Author), Mingze Xu (Author), Xiang Zhou (Author), Hongyu Guan (Author), Xun Zhu (Author), Yu Chen (Author), Kaiyuan Cao (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background It is well-established that understanding the mechanism of prostate cancer (PCa)-associated metastasis is paramount for improving its prognosis. Metastasis is known to involve the communication between tumor-associated macrophages (TAMs) and tumor cells. Exosomes are crucial in m...