Tetra-Primer ARMS PCR Optimization for Detection of IVS-II-I (G-A) and FSC 8/9 InsG Mutations in β-Thalassemia Major Patients in Isfahan Population

• Main Authors: Samaneh Hajihoseini (Author), Majid Motovali-Bashi (Author), Mohammad Amin Honardoost (Author), Nader Alerasool (Author)
• Formato: Livro
• Publicado em: Tehran University of Medical Sciences, 2015-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: β -thalassemia, a monogenic autosomal recessive disorder, is prevalent in Middle East, particularly in Iran. In Iran, near to 20 mutations in the β-globin gene are introduced as common mutations with varying incidence frequencies in each city. Therefore, detection and screening for coupl...