The effect of honokiol on pulmonary artery endothelium cell autophagy mediated by cyclophilin A in hypoxic pulmonary arterial hypertension

• Główni autorzy: Xiaoying Wang (Autor), Dandan Xiao (Autor), Cui Ma (Autor), Lixin Zhang (Autor), Qingya Duan (Autor), Xiaodong Zheng (Autor), Min Mao (Autor), Daling Zhu (Autor), Qian Li (Autor)
• Format: Książka
• Wydane: Elsevier, 2019-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abnormal autophagy plays critical roles in the structure and function of the pulmonary vasculature. Cyclophilin A (CyPA) can be secreted from cells in response to hypoxia and oxidative stress, which are involved in inducing autophagy and regulating the function of endothelial cells in pulmonary arte...