miR-301a-PTEN-AKT Signaling Induces Cardiomyocyte Proliferation and Promotes Cardiac Repair Post-MI

• Main Authors: Lixiao Zhen (Author), Qian Zhao (Author), Jinhui Lü (Author), Shengqiong Deng (Author), Zhen Xu (Author), Lin Zhang (Author), Yuzhen Zhang (Author), Huimin Fan (Author), Xiongwen Chen (Author), Zhongmin Liu (Author), Yuying Gu (Author), Zuoren Yu (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adult hearts are hard to recover after cardiac injury due to the limited proliferative ability of cardiomyocytes. Emerging evidence indicates the induction of cell cycle reentry of cardiomyocytes by special treatment or stimulation, which offers adult heart regenerative potential. Herein, a microRNA...