CYP2E1 deficit mediates cholic acid-induced malignant growth in hepatocellular carcinoma cells

• Main Authors: Zhiwei Hao (Author), Xuemin Liu (Author), Huanhuan He (Author), Zhixuan Wei (Author), Xiji Shu (Author), Jianzhi Wang (Author), Binlian Sun (Author), Hongyan Zhou (Author), Jiucheng Wang (Author), Ying Niu (Author), Zhiyong Hu (Author), Shaobo Hu (Author), Yuchen Liu (Author), Zhengqi Fu (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Increased level of serum cholic acid (CA) is often accompanied with decreased CYP2E1 expression in hepatocellular carcinoma (HCC) patients. However, the roles of CA and CYP2E1 in hepatocarcinogenesis have not been elucidated. This study aimed to investigate the roles and the unde...