BioSAXS Measurements Reveal That Two Antimicrobial Peptides Induce Similar Molecular Changes in Gram-Negative and Gram-Positive Bacteria

• Main Authors: Andreas von Gundlach (Author), Martin P. Ashby (Author), Jurnorain Gani (Author), Paula Matilde Lopez-Perez (Author), Alan Roy Cookson (Author), Sharon Ann Huws (Author), Christoph Rumancev (Author), Vasil M. Garamus (Author), Ralf Mikut (Author), Axel Rosenhahn (Author), Kai Hilpert (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Two highly active short broad-spectrum AMPs (14D and 69D) with unknown mode of action have been investigated in regards to their effect against the Gram-negative bacteria Escherichia coli and the Gram-positive bacteria methicillin-resistant Staphylococcus aureus (MRSA). Minimal inhibitory concentrat...