The use of proteasome inhibitors in anti-cancer therapy

• Hoofdauteurs: Marzena Teresa Baran (Auteur), Paulina Miziak (Auteur), Katarzyna Bonio (Auteur)
• Formaat: Boek
• Gepubliceerd in: Kazimierz Wielki University, 2020-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<p>Proteins are the basic building blocks of the human body. Most proteins, after fulfilling their function, are degraded with the help of a multi-catalytic proteolytic complex - the 26S proteasome, thanks to its prior labeling with a poly-ubiquitin chain. The ubiquitin-proteasome complex is i...