Dehydration affects drug transport over nasal mucosa

• Główni autorzy: Abdullah Ali (Autor), Marie Wahlgren (Autor), Birgitta Rembratt-Svensson (Autor), Ameena Daftani (Autor), Peter Falkman (Autor), Per Wollmer (Autor), Johan Engblom (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Formulations for nasal drug delivery often rely on water sorption to adhere to the mucosa, which also causes a higher water gradient over the tissue and subsequent dehydration. The primary aim of this study was therefore to evaluate mucosal response to dehydration and resolve the hypothesis that muc...