Loss of the Protein Cystathionine β-Synthase During Kidney Injury Promotes Renal Tubulointerstitial Fibrosis

• Main Authors: Xiangning Yuan (Author), Jin Zhang (Author), Feifei Xie (Author), Wenqing Tan (Author), Shuting Wang (Author), Ling Huang (Author), Lijian Tao (Author), Qiqi Xing (Author), Qiongjing Yuan (Author)
• Format: Book
• Published: Karger Publishers, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Renal tubulointerstitial fibrosis (TIF) is the common pathway of progressive chronic kidney disease. Inflammation has been widely accepted as the major driving force of TIF. Cystathionine β-synthase (CBS) is the first and rate-limiting enzyme in the transsulfuration pathway. CBS is...