Prostaglandin E2-Induced Cell Death is Mediated by Activation of EP2 Receptors in Motor Neuron-like NSC-34 Cells

• Main Authors: Hiroko Miyagishi (Author), Yasuhiro Kosuge (Author), Yuki Yoneoka (Author), Maiko Ozone (Author), Manami Endo (Author), Nobuhiro Osada (Author), Kumiko Ishige (Author), Kuniko Kusama-Eguchi (Author), Yoshihisa Ito (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Prostaglandin E2 (PGE2) was shown to induce neuronal death in the CNS. To characterize the neurotoxicity of PGE2 and E-prostanoid receptors (EP) in motor neurons, we investigated PGE2-induced cell death and the type(s) of EP responsible for mediating it in NSC-34, a motor neuron-like cell...