Birt-Hogg-Dubé syndrome in two Chinese families with mutations in the FLCN gene

• Main Authors: Xiaocan Hou (Author), Yuan Zhou (Author), Yun Peng (Author), Rong Qiu (Author), Kun Xia (Author), Beisha Tang (Author), Wei Zhuang (Author), Hong Jiang (Author)
• Format: Book
• Published: BMC, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Birt-Hogg-Dubé syndrome is an autosomal dominant hereditary condition caused by mutations in the folliculin-encoding gene FLCN (NM_144997). It is associated with skin lesions such as fibrofolliculoma, acrochordon and trichodiscoma; pulmonary lesions including spontaneous pneumot...