Model-based exploration of the rationality of off-label use of cetirizine in Chinese pediatric patients: a prospective cohort study

• Main Authors: Wei Liu (Author), Zhiyuan Tan (Author), Ping Yang (Author), Zhiheng Yu (Author), Xueting Yao (Author), Pengxiang Zhou (Author), Ling Liu (Author), Wei Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: Cetirizine is frequently administered at an increased dosage in clinical practice and recommended by several guidelines. Nonetheless, the pharmacokinetic (PK) profile and real-world safety data remain insufficient in the Chinese pediatric population. The objective of the current study is to de...