SOD1 Is an Integral Yet Insufficient Oxidizer of Hydrogen Sulfide in Trisomy 21 B Lymphocytes and Can Be Augmented by a Pleiotropic Carbon Nanozyme
Down syndrome (DS) is a multisystemic disorder that includes accelerated aging caused by trisomy 21. In particular, overexpression of cystathionine-β-synthase (CBS) is linked to excess intracellular hydrogen sulfide (H<sub>2</sub>S), a mitochondrial toxin at higher concentrations, which...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
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MDPI AG,
2024-11-01T00:00:00Z.
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