Hyper IgM syndrome presenting as chronic suppurative lung disease

• Main Authors: Montella Silvia (Author), Maglione Marco (Author), Giardino Giuliana (Author), Di Giorgio Angela (Author), Palamaro Loredana (Author), Mirra Virginia (Author), Ursini Matilde (Author), Salerno Mariacarolina (Author), Pignata Claudio (Author), Caffarelli Carlo (Author), Santamaria Francesca (Author)
• Format: Book
• Published: BMC, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>The Hyper-immunoglobulin M syndromes (HIGM) are a heterogeneous group of genetic disorders resulting in defects of immunoglobulin class switch recombination. Affected patients show humoral immunodeficiency and high susceptibility to opportunistic infections. Elev...