A Novel PD-L1-targeting Antagonistic DNA Aptamer With Antitumor Effects
The PD-1/PD-L1 axis is a major pathway involved in tumor immune evasion. Here, we report the novel PD-L1 antagonizing DNA aptamer (aptPD-L1) and demonstrate an integrated pipeline that expedites therapeutic aptamer development. Aptamer can exert antibody-mimic functions and is advantageous over anti...
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Main Authors: | , , , , |
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Format: | Book |
Published: |
Elsevier,
2016-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
Call Number: |
A1234.567 |
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Copy 1 | Available |