Dynamic MAPK signaling activity underlies a transition from growth arrest to proliferation in Drosophila scribble mutant tumors

• मुख्य लेखकों: Tiantian Ji (लेखक), Lina Zhang (लेखक), Mingxi Deng (लेखक), Shengshuo Huang (लेखक), Ying Wang (लेखक), Tri Thanh Pham (लेखक), Andrew Alan Smith (लेखक), Varun Sridhar (लेखक), Clemens Cabernard (लेखक), Jiguang Wang (लेखक), Yan Yan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2019-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Human tumors exhibit plasticity and evolving capacity over time. It is difficult to study the mechanisms of how tumors change over time in human patients, in particular during the early stages when a few oncogenic cells are barely detectable. Here, we used a Drosophila tumor model caused by loss of...