Advancing Cancer Therapy with Copper/Disulfiram Nanomedicines and Drug Delivery Systems

• Main Authors: Xuejia Kang (Author), Sanika Jadhav (Author), Manjusha Annaji (Author), Chung-Hui Huang (Author), Rajesh Amin (Author), Jianzhong Shen (Author), Charles R. Ashby (Author), Amit K. Tiwari (Author), R. Jayachandra Babu (Author), Pengyu Chen (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Disulfiram (DSF) is a thiocarbamate based drug that has been approved for treating alcoholism for over 60 years. Preclinical studies have shown that DSF has anticancer efficacy, and its supplementation with copper (CuII) significantly potentiates the efficacy of DSF. However, the results of clinical...