SIGLEC-1 in Systemic Sclerosis: A Useful Biomarker for Differential Diagnosis

• Main Authors: Jakob Höppner (Author), Vincent Casteleyn (Author), Robert Biesen (Author), Thomas Rose (Author), Wolfram Windisch (Author), Gerd Rüdiger Burmester (Author), Elise Siegert (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Systemic Sclerosis (SSc) is a clinically heterogeneous disease that includes an upregulation of type I interferons (IFNs). The aim of this observational study was to investigate the IFN-regulated protein Sialic Acid-Binding Ig-like Lectin 1 (SIGLEC-1) as a biomarker for disease phenotype, therapeuti...