Protein Modification Employing Non-Canonical Amino Acids to Prepare SUMOylation Detecting Bioconjugates

• Main Authors: Alexander C. Williard (Author), Hannah J. Switzer (Author), Christina A. Howard (Author), Rui Yin (Author), Brent L. Russell (Author), Ritwik Sanyal (Author), Shaun Yu (Author), Trinity M. Myers (Author), Brian M. Flood (Author), Oliver Kerscher (Author), Douglas D. Young (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein modification with non-canonical amino acids (ncAAs) represents a useful technology to afford homogenous samples of bioconjugates with site-specific modification. This technique can be directly applied to the detection of aberrant SUMOylation patterns, which are often indicative of disease st...