Vitamin D Promotes MSC Osteogenic Differentiation Stimulating Cell Adhesion and αVβ3 Expression

• Main Authors: Francesca Posa (Author), Adriana Di Benedetto (Author), Elisabetta A. Cavalcanti-Adam (Author), Graziana Colaianni (Author), Chiara Porro (Author), Teresa Trotta (Author), Giacomina Brunetti (Author), Lorenzo Lo Muzio (Author), Maria Grano (Author), Giorgio Mori (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vitamin D (Vit D) by means of its biological active form, 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), has a protective effect on the skeleton by acting on calcium homeostasis and bone formation. Furthermore, Vit D has a direct effect on mesenchymal stem cells (MSCs) in stimulating their osteogenic diff...