Recombinant Alpha-1 Antitrypsin as Dry Powder for Pulmonary Administration: A Formulative Proof of Concept

• मुख्य लेखकों: Annalisa Bianchera (लेखक), Esraa'a Alomari (लेखक), Annalisa Michielon (लेखक), Gianluca Bazzoli (लेखक), Nicoletta Ronda (लेखक), Giovanni Pighini (लेखक), Ilaria Zanotti (लेखक), Carmine Giorgio (लेखक), Andrea Mozzarelli (लेखक), Ruggero Bettini (लेखक), Stefano Bruno (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Alpha-1 antitrypsin (AAT) deficiency is a genetic disorder associated with pulmonary emphysema and bronchiectasis. Its management currently consists of weekly infusions of plasma-purified human AAT, which poses several issues regarding plasma supplies, possible pathogen transmission, purification co...