Fenofibrate (a PPAR-α Agonist) Administered During Ethanol Withdrawal Reverts Ethanol-Induced Astrogliosis and Restores the Levels of Glutamate Transporter in Ethanol-Administered Adolescent Rats

Fenofibrate (a PPAR-α Agonist) Administered During Ethanol Withdrawal Reverts Ethanol-Induced Astrogliosis and Restores the Levels of Glutamate Transporter in Ethanol-Administered Adolescent Rats

High-ethanol intake induces a neuroinflammatory response, which has been proposed as responsible for the maintenance of chronic ethanol consumption. Neuroinflammation decreases glutamate transporter (GLT-1) expression, increasing levels of glutamate that trigger dopamine release at the corticolimbic...

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Main Authors: Francisca Villavicencio-Tejo (Author), Osvaldo Flores-Bastías (Author), Lucas Marambio-Ruiz (Author), Diliana Pérez-Reytor (Author), Eduardo Karahanian (Author)
Format: Book
Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
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