A phase 1 randomized study of hemodynamic effects and pharmacokinetic interactions during concomitant use of rimegepant and sumatriptan in healthy adults

• Main Authors: Robert Croop (Author), Andrea Ivans (Author), Matt S Anderson (Author), Joseph Stringfellow (Author), Richard Bertz (Author), Michael Hanna (Author), Francine Healy (Author), David A Stock (Author), Vladimir Coric (Author), Richard B Lipton (Author)
• Format: Book
• Published: SAGE Publishing, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This randomized, partially-blinded, placebo-controlled study evaluated hemodynamic effects, pharmacokinetic interactions, and safety of concomitant administration of oral rimegepant and subcutaneous sumatriptan. Methods: Healthy non-smokers aged ≥18 and ≤40 years (men) or ≥18 and ≤50 year...