Jiang Tang Xiao Ke Granule Play an Anti-diabetic Role in Diabetic Mice Pancreatic Tissue by Regulating the mRNAs and MicroRNAs Associated with PI3K-Akt Signaling Pathway

• Main Authors: Fang-Fang Mo (Author), Tian An (Author), Zi-Jian Zhang (Author), Yu-Fei Liu (Author), Hai-Xia Liu (Author), Yan-Yun Pan (Author), Jia-Nan Miao (Author), Dan-Dan Zhao (Author), Xiu-Yan Yang (Author), Dong-Wei Zhang (Author), Guang-Jian Jiang (Author), Si-Hua Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: To investigate the effect of JTXK granule on the expression pattern of miRNA in pancreatic tissue of KKAy diabetic mice, and to explore the molecular mechanism and pathways of JTXK granule in anti-diabetic effect.Methods: We used high fat diet (HFD) to induce the KKAy diabetic mice and scre...