Lower BCL11B expression is associated with adverse clinical outcome for patients with myelodysplastic syndrome

• Main Authors: Xin Huang (Author), Cunte Chen (Author), Mengjun Zhong (Author), Suxia Geng (Author), Yujie Zhao (Author), Minming Li (Author), Chenxin Deng (Author), Lingji Zeng (Author), Ping Wu (Author), Zesheng Lu (Author), Jianyu Weng (Author), Xin Du (Author), Yangqiu Li (Author)
• Format: Book
• Published: BMC, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Myelodysplastic syndrome (MDS) is an aggressive and genetically heterogeneous disease with poor prognosis. Cellular immune disorder is a common characteristic of this disease and is thought to be related to clinical outcome. Alterations in T cell clonal expansion and T cell dysfunction has...