Size and Flexibility Define the Inhibition of the H3N2 Influenza Endonuclease Enzyme by Calix[n]arenes

Size and Flexibility Define the Inhibition of the H3N2 Influenza Endonuclease Enzyme by Calix[n]arenes

Inhibition of H3N2 influenza PA endonuclease activity by a panel of anionic calix[n]arenes and β-cyclodextrin sulfate has been studied. The joint experimental and theoretical results reveal that the larger, more flexible and highly water-soluble sulfonato-calix[n]arenes have high inhibitory activity...

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Main Authors: Yannick Tauran (Author), José Pedro Cerón-Carrasco (Author), Moez Rhimi (Author), Florent Perret (Author), Beomjoon Kim (Author), Dominique Collard (Author), Anthony W. Coleman (Author), Horacio Pérez-Sánchez (Author)
Format: Book
Published: MDPI AG, 2019-06-01T00:00:00Z.
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3rd Floor Main Library

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