BRCA-mutated gastric adenocarcinomas are associated with chromosomal instability and responsiveness to platinum-based chemotherapy
Background Homologous recombination defect is an important biomarker of chemotherapy in certain tumor types, and the presence of pathogenic or likely pathogenic mutations involving BRCA1 or BRCA2 (p-BRCA) mutations is the most well-established marker for the homologous recombination defect. Gastric...
Saved in:
Main Authors: | Ji Hyun Oh (Author), Chang Ohk Sung (Author), Hyung-Don Kim (Author), Sung-Min Chun (Author), Jihun Kim (Author) |
---|---|
Format: | Book |
Published: |
Korean Society of Pathologists & the Korean Society for Cytopathology,
2023-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Clinical Utility of a Fully Automated Microsatellite Instability Test with Minimal Hands-on Time
by: Miseon Lee, et al.
Published: (2019) -
Resistance to PARP Inhibitors After First-Line Platinum-Based Chemotherapy in a Patient with Advanced Ovarian Cancer with a Pathogenic Somatic BRCA1 Mutation
by: Zhong L, et al.
Published: (2023) -
Site-agnostic PARP-inhibitor maintenance therapy of advanced stage BRCA2-mutated gastric-type endocervical adenocarcinoma: A case report
by: Lauren Jill Tostrud, et al.
Published: (2024) -
BRCA1 and BRCA2 Mutations Diagnostic and Therapeutic Implications
Published: (2023) -
UBE2C Is a Potential Biomarker of Intestinal-Type Gastric Cancer With Chromosomal Instability
by: Jun Zhang, et al.
Published: (2018)