BRCA-mutated gastric adenocarcinomas are associated with chromosomal instability and responsiveness to platinum-based chemotherapy
Background Homologous recombination defect is an important biomarker of chemotherapy in certain tumor types, and the presence of pathogenic or likely pathogenic mutations involving BRCA1 or BRCA2 (p-BRCA) mutations is the most well-established marker for the homologous recombination defect. Gastric...
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Main Authors: | , , , , |
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Format: | Book |
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Korean Society of Pathologists & the Korean Society for Cytopathology,
2023-11-01T00:00:00Z.
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