TLR9-adjuvanted pneumococcal conjugate vaccine induces antibody-independent memory responses in HIV-infected adults

HIV-patients have excess of pneumococcal infection. We immunized 40 HIV-patients twice with pneumococcal conjugate vaccine (Prevnar, Pfizer) +/− a TLR9 agonist (CPG 7909). Peripheral blood mononuclear cells were stimulated with pneumococcal polysaccharides and cytokine concentrations measured. The C...

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Bibliographic Details
Main Authors: Rasmus Offersen (Author), Jesper Melchjorsen (Author), Søren R. Paludan (Author), Lars Østergaard (Author), Martin Tolstrup (Author), Ole S. Søgaard (Author)
Format: Book
Published: Taylor & Francis Group, 2012-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available