The Effect of Natural Health Products and Traditional Medicines on the Activity of Human Hepatic Microsomal-Mediated Metabolism of Oseltamivir
Purpose. Oseltamivir is a prodrug that requires metabolic activation but there is little information on whether natural health products interact to prevent the biotransformation by the carboxylesterase. Methods. HPLC-DAD-ESI-MSD and fluorometric assays were used to determine if 50-pooled mixed gende...
Saved in:
Main Authors: | Rui Liu (Author), Teresa W Tam (Author), Jingqin Mao (Author), Ammar Saleem (Author), Anthony Krantis (Author), John T Arnason (Author), Brian C Foster (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2010-02-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Cytochrome P450 3A4 and 2D6-Mediated Metabolism of Leisure and Medicinal Teas
by: Teresa W Tam, et al.
Published: (2014) -
Enantioselective metabolism of hydroxychloroquine employing rats and mice hepatic microsomes
by: Carmem Dickow Cardoso, et al.
Published: (2009) -
Reversible, Time-Dependent Inhibition of CYP3A-Mediated Metabolism of Midazolam and Tacrolimus by Telaprevir in Human Liver Microsomes
by: Brian Chapron, et al.
Published: (2015) -
The Metabolism and Transplacental Transfer of Oseltamivir in the Ex Vivo Human Model
by: Kevin C. Worley, et al.
Published: (2008) -
Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers
by: Jang K, et al.
Published: (2017)