A Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometric Assay for the Quantification of Fabry Disease Biomarker Globotriaosylceramide (GB3) in Fabry Model Mouse

• المؤلفون الرئيسيون: Seok-Ho Shin (مؤلف), Min-Ho Park (مؤلف), Jin-Ju Byeon (مؤلف), Byeong ill Lee (مؤلف), Yuri Park (مؤلف), Ah-ra Ko (مؤلف), Mi-ran Seong (مؤلف), Soyeon Lee (مؤلف), Mi Ra Kim (مؤلف), Jinwook Seo (مؤلف), Myung Eun Jung (مؤلف), Dong-Kyu Jin (مؤلف), Young G. Shin (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2018-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Fabry disease is a rare lysosomal storage disorder resulting from the lack of α-Gal A gene activity. Globotriaosylceramide (GB3, ceramide trihexoside) is a novel endogenous biomarker which predicts the incidence of Fabry disease. At the early stage efficacy/biomarker study, a rapid method...